More than half of American adults were not worried about flu season, research shows

With flu-related hospitalizations rising to record early-season levels, the American Heart Association, a global force for longer, healthier lives for all, is concerned that many people will be caught off guard by this health threat and urges on rapid vaccination against the virus. According to a survey conducted by The Harris Poll commissioned by the … Read more

An analysis of the dynamics of COVID-19, its impact on different age groups, anti-vaxxers and reinfection

Previous studies have reported age-related differences in the tolerance and responsiveness of the 2019 coronavirus disease (COVID-19) disease, with younger individuals generally having better outcomes than older people. In addition, age-targeted COVID-19 mitigation strategies have been reported to significantly reduce intensive care unit (ICU) admissions and deaths. In a recent Scientific Reports In a journal … Read more

Model study provides a public health roadmap to maximize the impact of monkeypox vaccines

A pilot study to investigate the optimal allocation of vaccines against monkeypox virus (MPXV) provides a public health roadmap to maximize the impact of a limited supply of vaccines. The article, published in CMJ (Journal of the Canadian Medical Association) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.221232, confirms that prioritizing vaccines to larger networks with more initial infections and greater spread … Read more

Are Nasal Spray Vaccines the Solution to Respiratory Infectious Diseases?

A recent study published in the journal Trends in molecular medicine reviewed current efforts in developing nasal vaccines, delivery systems, and clinical applications for the prevention of respiratory disease. Review: Nasal Vaccines: Solutions to Respiratory Infectious Diseases. Image credit: Josep Suria / Shutterstock Introduction Mucosal surfaces are exposed to external environments and serve as primary … Read more

Memory B and T cell responses differ when induced by SARS-CoV-2 infections or booster vaccinations

In a recent study published in The Journal of Immunology, a team of researchers from Japan examined the memory B and T cell responses to the spike protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after the booster dose of the 2019 coronavirus disease (COVID-19) messenger ribonucleic acid (mRNA) vaccine BNT162b2. They also … Read more

Nanoparticles displaying SARS-CoV-1 and SARS-CoV-2 peaks induce broad antibody responses in animal models

A recent study published in the journal iScience reported that nanoparticles (NPs) displaying spike proteins from different sarbecoviruses together enhance the breadth of neutralizing reactions. Coronavirus disease 2019 (COVID-19) vaccines are based on the spike protein of the Wuhan-Hu-1 strain, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Mutant variants of SARS-CoV-2 are less sensitive … Read more

Measles becomes ‘an imminent global threat’ due to the Covid pandemic: WHO

The World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) said Wednesday (local time) that measles immunization had dropped significantly since the start of the coronavirus pandemic, resulting in a record high of nearly 40 million children missing a vaccine dose last year. “There is now an imminent threat … Read more

Researchers test mRNA technology for universal flu vaccine

Nov 24 (Reuters) – An experimental vaccine provided broad protection against all 20 known subtypes of the influenza A and B virus in initial tests in mice and ferrets, potentially opening a path to a universal flu shot that could help future pandemics prevent, according to a US. study published on Thursday. The two-dose vaccine … Read more

Do previously infected people still benefit from vaccination against COVID-19?

In a recent study published in PLOS medicine, researchers determined the vaccine effectiveness (VE) of the primary vaccination course for coronavirus disease 2019 (COVID-19). They determined VE against reinfection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19-related hospitalization and mortality. In this way, the researchers assessed the effect of time since vaccination during the … Read more

The relationship between neutralization levels and observed efficacy against asymptomatic and symptomatic infection of ten COVID-19 vaccines

In a recent study published on the medRxiv* server, researchers determined whether levels of neutralizing antibodies (NAb) were predictive of the efficacy of fractional vaccine doses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Study: Predictive efficacy of vaccine dose fractionation using neutralizing antibody levels. Image credit: peterschreiber.media/Shutterstock Background During the 2016 yellow fever … Read more