New technologies and recent advances in the study of T cells and T cell epitope discovery in food allergy research

Although food allergies have been widespread for many years, their incidence has recently increased. In a recent study, scientists reviewed the latest technological advancements and the discovery of T cell epitope associated with food allergy. This review is available in the Journal of Allergy and Clinical Immunology. Study: Discovery of T cell epitope and single … Read more

Approved and development of passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

In a recent study published in Journal of Pediatricsresearchers investigated active and passive childhood vaccination against respiratory syncytial virus (RSV). Study: Current strategies and perspectives for active and passive immunization against respiratory syncytial virus in childhood. Image credit: ART-ur/Shutterstock Background Despite the global importance of RSV infections in children, only one monoclonal antibody, Palivizumab, has … Read more

Does flu vaccination reduce death and vascular events in heart failure patients?

In a recent study published in The Lancet Global Healthresearchers conducted a placebo-controlled, double-blind clinical trial to assess whether influenza vaccination effectively reduced vascular events and mortality in patients with heart failure. Study: Influenza vaccine to reduce adverse vascular events in heart failure patients: a multinational randomized, double-blind, placebo-controlled trial. Image credit: antoniodiaz/Shutterstock Background Heart … Read more

Does fenofibrate improve clinical outcomes in patients with COVID-19?

In a recent study published in Nature Metabolismresearchers assessed the effect of fenofibrate on acute coronavirus disease 2019 (COVID-19). Study: A randomized clinical trial of modulation of lipid metabolism with fenofibrate for acute coronavirus disease 2019. Image Credit: luchschenF/Shutterstock Background Previous studies have shown that the cytotoxicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) … Read more

Monoclonal antibody shows efficacy in preventing malaria infection in African adults

A dose of an antibody drug safely protected healthy, non-pregnant adults from malaria infection during an intense six-month malaria season in Mali, Africa, a National Institutes of Health clinical study has found. The antibody was up to 88.2% effective in preventing infection over a 24-week period, demonstrating for the first time that a monoclonal antibody … Read more

Clinical trial to evaluate antiviral drug for monkeypox begins in Democratic Republic of Congo

A clinical trial has begun in the Democratic Republic of Congo (DRC) to evaluate the antiviral drug tecovirimat, also known as TPOXX, in adults and children with monkeypox. The trial will evaluate the drug’s safety and its ability to reduce monkeypox symptoms and prevent serious consequences, including death. The National Institute of Allergy and Infectious … Read more

Clinical study to test the safety and efficacy of bacteriophages for the treatment of P. aeruginosa infections in CF patients

Cystic fibrosis (CF) is an inherited condition that causes severe damage to the lungs and other organs in the body. Nearly 40,000 children and adults in the United States are living with CF, an often difficult existence exacerbated by an opportunistic bacteria called Pseudomonas aeruginosawhich is a leading cause of chronic, life-threatening lung infections. P. … Read more

Healthy people with high cholesterol don’t benefit from statins, study says

According to 2020 data from the American Heart Association, about 40 million adults in the United States regularly take statins to lower their cholesterol levels and reduce their risk of heart disease and stroke. However, many of them do not benefit from these drugs based on new research from David Diamond, a neuroscientist and cardiovascular … Read more

What is the effect of pomegranate extract consumption on satiety parameters?

A recent article published in food found that the intake of pomegranate extract and juice can reduce appetite as measured by satiety parameters. Study: effect of pomegranate extract consumption on satiety parameters in healthy volunteers: a preliminary randomized trial. Image Credit: Agave Studio/Shutterstock Background Obesity is a multifactorial disease and its co-morbidities place a significant … Read more

The effectiveness of three recycled drugs in preventing severe SARS-CoV-2 infection in non-hospitalized adults

In a recent study published in NEJMResearchers conducted a phase III clinical trial to test the effectiveness of three recycled drugs – metformin, ivermectin and fluvoxamine, in preventing progression to severe coronavirus disease 2019 (COVID-19). Study: Randomized trial of metformin, ivermectin and fluvoxamine for Covid-19. Image credit: robert coolen/Shutterstock Background Current vaccines and clinical treatments … Read more